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Understanding hydrocarbon migration and accumulation mechanisms is one of the key scientific problems that should be solved for effective hydrocarbon exploration in the superimposed basins developed in northwest China. The northwest striking No.1 slope break zone, which is a representative of superimposed basins in the Tarim Basin, can be divided into five parts due to the intersection of the northeast strike-slip faults. Controlled by the tectonic framework, the types and properties of reservoirs and the hydrocarbon compositions can also be divided into five parts from east to west. Anomalies of all the parameters were found on the fault intersection zone and weakened up-dip along the structural ridge away from it. Thus, it can be inferred that the intersection zone is the hydrocarbon charging position. This new conclusion differs greatly from the traditional viewpoint, which believes that the hydrocarbon migrates and accumulates along the whole plane of the No.1 slope break zone. The viewpoint is further supported by the evidence from the theory of main pathway systems, obvious improvement of the reservoir quality (2-3 orders of magnitude at the intersection zone) and the formation mechanisms of the fault intersection zone. Differential hydrocarbon migration and entrapment exists in and around the strikeslip faults. This is controlled by the internal structure of faults. It is concluded that the more complicated the fault structure is, the more significant the effects will be. If there is a deformation band, it will hinder the cross fault migration due to the common feature of two to four orders of magnitude reduction in permeability. Otherwise, hydrocarbons tend to accumulate in the up-dip structure under the control of buoyancy. Further research on the internal fault structure should be emphasized.